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No Priors
Elad Gil and Sarah Guo speak with leading AI engineers, researchers, and founders about model progress, markets at risk of disruption, and how commerce, culture, and society may change.
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Redefining Chip Architecture with Arm CEO Rene Haas
Arm moved from IP licensing into physical silicon with the Arm AGI CPU after Meta sought a general-purpose agentic CPU no one else could provide.AI reaches 80% to 90% of engineers, while Arm’s documentation and test benches may make proprietary IP more trainable; supply may remain constrained for 3 to 5 years, with data-center construction a possible next bottleneck.
Rethinking Legacy Data Infrastructure with Eon Co-Founders Ofir Ehrlich and Gonen Stein
Elad GilOfir EhrlichGonen Stein
Models and compute have almost zero switching cost; accumulated enterprise data is becoming the moat, underscored by Google’s $10M purchase of bankrupt Spirit Airlines’ data.Eon maps and classifies siloed data, controls sensitive access, and exposes it to AI without compromising production or compliance, while agentic permissions create extreme-velocity ransomware risk and most companies still do not use AI.
From Restoring Sight to Reimagining the Brain, with Max Hodak
Prima won CE marketing approval in Europe in July, with commercial sales expected in coming weeks after trials let patients with macular degeneration complete Sudoku, crosswords, and read books.Science acquired Pixium’s Stanford-originated implant after about two years, calling it “by far the state-of-the-art”; pricing is unset, while future versions could improve color and expand the population from hundreds of thousands to millions.
Building a $200M Bootstrapped Chess Empire with Chess.com CEO Erik Allebest
Chess.com is on track for a little over $200 million in revenue this year with 10M DAU, 40–50M MAU and 250M+ registered members, achieved without primary capital after a $56K 2005 domain purchase.Cash-flow-funded product and community compounding lifted the baseline through successive demand waves, while the secondary-only CVC deal and General Atlantic reinvestment improved operational maturity.Gambit and the billion-player ambition extend expansion paths, while cheating enforcement and AI governance remain risks to monitor.
Chasing Trillion-Dollar Companies, Founder Ambition, Token Budgets, & Regulatory Capture
Anthropic, OpenAI, and SpaceX’s leap toward $1 trillion is a five-year anomaly, while reaching that scale likely requires $50 billion-$100 billion of revenue with good margins.AI’s opportunity may be far larger than current per-seat models imply, but compute bottlenecks, founder exit timing, recursive-self-improvement uncertainty, and token allocation by return on invested tokens remain decisive constraints.
Building an Autonomous Enterprise for Real-World Services with Netic Founder Melisa Tokmak
Netic has moved beyond call overflow: over 70% of customers are now “Netic first,” with agents determining service urgency, equipment, customer value, and the right worker across essential-service businesses.A $500,000 contract closed end-to-end in 14 days, and Tokmak estimates over $600 million in customer value from AI-handled interactions; the open question is whether vertical orchestration can compound faster than general-purpose labs or services roll-ups.
Building an Autonomous Delivery Experience with DoorDash Co-Founders Andy Fang and Stanley Tang
Sarah GuoAndy FangStanley Tang
Ask DoorDash is shifting demand, with 50% of restaurant-order trajectories reaching new-to-customer venues and grocery baskets roughly 40% larger.DoorDash’s 10 billion delivery history supplies pickup and handoff ground truth for routing DOT, drones and Dashers, but scaling now depends on hardware, operations and supply chains rather than autonomy alone.
Travel Through the Lens of AI with with Booking.com CEO Glenn Fogel
Booking’s Penny is emerging as a personalized travel concierge, with adoption reportedly doubling monthly and a stronger long-term opportunity in repairing disrupted itineraries than merely shortening search.The investment test is still unresolved: token costs, routing, conversion, cancellations, loyalty, and lifetime value must justify roughly $700 million of annual multi-initiative spending, while scale remains an advantage rather than a moat.
How Nuclear Will Unlock Energy Abundance with Valar Atomics Founder Isaiah Taylor
Valar Atomics treats nuclear as a manufacturing problem, targeting a simple, intrinsically safe “Toyota Camry” rather than a bespoke paper reactor.DOE testing authority enabled its 100 kW W-250 to reach criticality, while passive heat removal and a seven-month milestone interval provide operating evidence.Equity-funded deployment could precede project finance, with AI as an initial catalyst and cheaper energy as the longer-term demand thesis.
Really Big Test-Time Compute in AI Changes Benchmarks, Safety and Research with OpenAI's Noam Brown
Noam Brown argues that model quality must be measured as a cost, token, or time curve, because fixed benchmark scores hide gains from test-time compute.Models can keep improving beyond 100 million tokens, while safety policies still lack a clear budget for evaluating cyber, bio, and other dangerous capabilities.Routing and orchestration businesses therefore face a demanding test: outperforming a single stronger model allowed to think longer at the same cost, with gains that transfer beyond benchmarks.









