Harry Stebbings × Jack Altman

Instinct’s $1 billion round at a $10 billion valuation raises the bar for defensible economics before compute costs overwhelm the company.Miro’s sale to Bending Spoons for roughly $1.35 billion after a $17.5 billion valuation shows positive cash flow cannot prevent late-stage SaaS repricing, while Mistral’s €3 billion round underscores AI’s European sovereignty agenda.

Bill Ackman × Shane Parrish

AI is transformational but bubble-like, with one startup’s valuation jumping from $400 million to $1 billion in two weeks and another reaching $5 billion in Series A.Cognition’s claimed COBOL modernization in days could lower bank costs, but pricing power determines whether shareholders retain the savings.Ackman therefore emphasizes disciplined capital use, continual moat reassessment, and exiting when confidence—not merely price—breaks.

Anish Acharya × David Pawlan

AI assistants may win by recovering “free money”—HSA reimbursements, fare credits, or 50% lower water bills—not by abstract productivity gains.Proactivity can be a moat when agents act invisibly, but one unauthorized insurance switch could destroy trust.At roughly $20 per user per day for ambitious browser-driven services, economics may require narrow agents priced at $200-$300—or eventually $1,000—a month.

庄明浩 × 严华

EDA虽规模较小，却是芯片设计不可绕开的平台，新思科技长期占据约40%-50%份额。设计周期压缩至12-15个月，AI推理ASIC、multi-die和系统级仿真或带来新需求，但Agent收费、FDE交付及最终sign-off仍待观察。

Ben Thompson × Andrew Sharp

Meta’s Muse gives its portfolio a missing anchor: AI models become the number two, glasses the number three, and hardware becomes Muse delivery devices rather than standalone AR/VR.Nat Friedman’s return and a new product team underpin execution, while $1,200–$1,300 glasses and a possible holiday Tamagotchi point to a potentially winner-take-all consumer platform—only two weeks in.

Harry Stebbings × Daniel Dines

Daniel Dines argues enterprise AI will diffuse process by process, because models retain context without being transformed by experience, while “millions of Einsteins” are not yet hireable people.The investable asset is the portable “map of work,” with AI designing deterministic, governed software around probabilistic models; UiPath’s 14% growth and production gaps in vibe-coded procurement tools leave timing and near-free human replacements as key risks.

Adam Foroughi

AppLovin is extending a roughly $50B mobile-gaming ad market, with platform ad spend growing from $11B to about $20B, into e-commerce discovery.Its April 2023 deep-learning model improved advertiser performance and enabled scaling, while roughly $6B in buybacks retired 20–25% of shares after a 92% drawdown.Discovery may expand activity beyond Google Search, but stated 84% EBITDA margins depend on differentiated data, complexity and scale.

Harry Stebbings

Instinct’s $1B raise at a $10B valuation pairs minute-long latency with compute costs: 10M users paying $10 monthly imply a $1.2B annual burden.Jason’s reversal—from recommending the round to refusing it—alongside Miro’s $1.3B sale from $17.5B and Canva’s slowdown from 30% to 20%, highlights SaaS’s shift from revenue multiples to EBITDA.

Satya Nadella

Persistent AI agents create a new insider-risk category: even mundane enterprise tasks could trigger reward hacking or falsified books.Behavioral monitoring, full auditability, and causal or semantic verification are the proposed response, while cheaper models shift margin toward applications and middleware.Microsoft’s “use all but be independent of all” strategy makes interoperability an adoption catalyst, but 7–8% broad-based GDP growth and social license remain tests.

Chamath Palihapitiya × Jason Calacanis × David Sacks × David Friedberg × Gwynne Shotwell × Elon Musk

Cross-lab AI peer review would give competitors pre-release API access to run logged safety harnesses, making distillation visible and raising reputational and product-liability stakes.Compute rental has become SpaceX’s “heck of a business,” with no drop in demand, while Starlink penetration remains 1.5–2%.Terafab and Starship’s flight 15 tower-catch attempt are milestones amid Taiwan supply risk and infrastructure constraints.